Those wide, staring eyes made me click on this, and I was not disappointed - the entire thing is filled with crazy eyes. I'd like to know what the story is about... The "kuru" in the title led me to the neurodegenerative disease of the same name, but the "kuru kuru" the first 2 kanji represent translate as "crazy" - maybe retitle as "Crazy Eientei"? edit: Thanks for the link, ISBML - the story is way darker than I could've guessed, with a typically "bad end."
http://danbooru.donmai.us/pools/10985 You can read there is you wish. To summarize, Reisen is self medicating for PTSD, Tewi is trying to help her (without meds), Eirin is trying to make a cure, and Kaguya is trying to keep people sane.