If it's name is "TS Syndrome" is the name, it's likely Gender Bender(TS as in Transexual, I've noticed lots of japanese sites use it to describe all gender bender, though it commonly refers to 'shemales' or post-ops here). And even without 'process' of any kind, we can make that guess by the way things play out(looks like the guy in 'sporty sunglasses' gets TGed at one point, and most importantly, the first pic implies the main character was a guy.
According to the first page, and my poor japanese: "One day in June, I woke up and found that I had become a girl." "TS Disease... lately it's been pretty common to hear about it."